they don’t work instantly and usually take a couple or few doses to work, they don’t make you explosive so don’t worry, they will allow you to go the toilet rather than make you go, so when you feel you need to they will make it so you can, its unlikely you’ll be runing desperatly to the toilet. take them any time, sooner you take them the sooner you can feel better, remember to drink loads of fluids aswell and when you feel up to it to move about as it will help move things along aswell x