hi Rachel, i went for my surgeon check up at 7 weeks post op, and was given the go ahead to wear underwire bras. However they just didn’t feel comfortable, so i didn’t actually start wearing underwires untill i was 9 weeks post op! Even then, for the first week i alternated wearing underwire one day and sports bra the next day. You just need to see how they feel hun. Sorry, can’t help about the running question lol as i never run! Hope this helps x